The Indian Journal of Critical Care Medicine's 2023, volume 27, number 2, contained the articles from pages 135-138.
A study by MC Anton, B Shanthi, and E Vasudevan aimed to determine the prognostic cut-off values of the coagulation analyte D-dimer for ICU admission among COVID-19 patients. The Indian Journal of Critical Care Medicine, in its 2023 second volume, issue 2, published articles from page 135 to 138.
In 2019, the Neurocritical Care Society (NCS) launched the Curing Coma Campaign (CCC) to foster collaboration among coma scientists, neurointensivists, and neurorehabilitation professionals from varied backgrounds.
This campaign seeks to transcend the restrictions imposed by current definitions of coma, identifying ways to improve prognostication, locating applicable therapeutic approaches, and significantly impacting clinical outcomes. At this time, the comprehensive approach adopted by the CCC seems both ambitious and challenging in its entirety.
The veracity of this statement appears restricted to the Western sphere, encompassing regions like North America, Europe, and certain advanced countries. Nonetheless, the entirety of the CCC principle could be challenged in lower-middle-income states. Future prospects for India, as envisioned in the CCC, hinge on overcoming several obstacles that can and should be tackled.
India's prospective difficulties are the focal point of this article's examination.
The authorship team comprised I Kapoor, C Mahajan, KG Zirpe, S Samavedam, TK Sahoo, and H Sapra.
Within the Indian Subcontinent, there are concerns regarding the Curing Coma Campaign. Pages 89 to 92 of the Indian Journal of Critical Care Medicine, 2023, volume 27, issue 2, are dedicated to specific articles.
Researchers I. Kapoor, C. Mahajan, K.G. Zirpe, S. Samavedam, T.K. Sahoo, H. Sapra, and other contributing personnel were involved. In the Indian Subcontinent, the Curing Coma Campaign presents some concerns. The Indian Journal of Critical Care Medicine, 2023, volume 27, issue 2, featured content from pages 89 to 92.
A growing number of melanoma patients are benefiting from nivolumab therapy. Nonetheless, the use of this is accompanied by the possibility of substantial side effects that can affect every organ system. A documented case demonstrates how nivolumab therapy resulted in severe and extensive diaphragm impairment. Because nivolumab is being used more often, these types of complications are predicted to become more frequent occurrences, demanding all clinicians be attentive to their possibility in patients receiving nivolumab therapy who present with dyspnea. Diaphragm dysfunction can be diagnosed with the use of the readily available ultrasound procedure.
In the context of this discussion, JJ Schouwenburg. A Detailed Case Report on Nivolumab-Related Diaphragm Dysfunction. The Indian Journal of Critical Care Medicine, within its 2023, volume 27, number 2, presented an article in the 147-148 page range.
In particular, JJ Schouwenburg. Investigating Nivolumab's Impact on Diaphragmatic Function: A Case Report. The Indian Journal of Critical Care Medicine, issue 2, volume 27 of the 2023 publication, discusses critical care medicine on pages 147-148.
Determining the role of ultrasound-guided initial fluid resuscitation and clinical decision-making in reducing post-resuscitation fluid overload in pediatric septic shock cases by day three.
A randomized, controlled, open-label, superiority trial, conducted in the PICU of a government-funded tertiary care hospital in eastern India, was prospective and employed a parallel limb design. GW3965 cost The study's patient enrollment period covered the duration from June 2021 to March 2022. A study randomized fifty-six children with verified or suspected septic shock, aged one month to twelve years, to receive either ultrasound-guided or clinically guided fluid boluses (11 to 1 ratio), followed by outcome evaluation. The frequency of fluid overload on the third day of admission served as the primary outcome measure. Ultrasound-guided fluid boluses, alongside clinical direction, comprised the treatment regimen for one group, while the other, the control group, received identical fluid boluses, but without ultrasound guidance, up to a maximum of 60 mL/kg.
The ultrasound group exhibited a significantly reduced incidence of fluid overload on the third day of admission, with 25% experiencing the condition compared to 62% in the control group.
The median (interquartile range) cumulative fluid balance percentage on day three was 65% (range 33-103%) in the first group, versus 113% (range 54-175%) in the second group.
Return a JSON list of ten distinct sentences, each structurally altered and uniquely worded in contrast to the original input sentence. The ultrasound findings showed a significantly smaller volume of fluid bolus administered, 40 mL/kg (range 30-50) median versus 50 mL/kg (range 40-80) median.
Each sentence is a meticulously crafted expression, demonstrating a profound understanding of linguistic principles. The ultrasound group exhibited a reduced resuscitation time compared to the control group (134 ± 56 hours versus 205 ± 8 hours).
= 0002).
Preventing fluid overload and its complications in children with septic shock saw a marked improvement with the utilization of ultrasound-guided fluid boluses over clinically guided therapy. Ultrasound's potential utility in pediatric septic shock resuscitation within the PICU is underscored by these contributing factors.
Raut SK, Mahapatra MK, Uz Zaman MA, Roy O, Kaiser RS, and Sarkar M.
A research project contrasting the results of ultrasound-guided and clinically-directed fluid management in children with septic shock. The 2023 second volume, issue 2 of the Indian Journal of Critical Care Medicine highlights findings presented on pages 139-146.
Researchers Kaiser RS, Sarkar M, Raut SK, Mahapatra MK, Uz Zaman MA, and Roy O, along with others (et al.). An investigation into the relative effectiveness of ultrasound-guided and clinically-directed fluid therapies for children with septic shock. GW3965 cost The second issue of the 2023 Indian Journal of Critical Care Medicine, volume 27, presented the research articles from page 139 to page 146.
The use of recombinant tissue plasminogen activator (rtPA) has brought about a significant improvement in the management of acute ischemic stroke. Shorter door-to-imaging and door-to-needle times are directly correlated with improved results in thrombolysed patients. An observational study was conducted to determine the door-to-imaging time (DIT) and door-to-non-imaging-treatment time (DTN) for all patients who had undergone thrombolytic therapy.
At a tertiary care teaching hospital, a cross-sectional observational study followed 252 acute ischemic stroke patients over 18 months; 52 of these patients underwent rtPA thrombolysis. The interval between reaching neuroimaging and initiating thrombolysis was noted for each patient.
Amongst the total patients who received thrombolytic therapy, only ten underwent neuroimaging (non-contrast computed tomography (NCCT) head with MRI brain screen) within 30 minutes of hospital arrival, followed by 38 patients within the 30-60 minute range and two patients each in the 61-90 and 91-120 minute intervals. Three patients had a DTN time of 30-60 minutes; 31 patients were thrombolysed within the 61-90 minute window, with additional thrombolysed patients within 91-120 minute, 121-150 minute, and 151-180 minute ranges of 7 and 5 each, respectively. One patient's DTN time was measured between 181 and 210 minutes inclusive.
Most patients in the study underwent neuroimaging procedures within 60 minutes of hospital arrival, and thrombolysis was conducted afterward, usually within 60 to 90 minutes. GW3965 cost Indian tertiary care centers' stroke management protocols, though not following the ideal timeframes, require significant improvements and streamlining efforts.
In their work, 'Stroke Thrombolysis: Beating the Clock,' Shah A and Diwan A analyze a critical issue. The second issue of the Indian Journal of Critical Care Medicine's 27th volume (2023) contains articles found on pages 107 through 110.
A. Shah and A. Diwan explore the timely aspects of stroke thrombolysis. The Indian Journal of Critical Care Medicine, in its 2023 second issue of volume 27, published an article spanning pages 107 to 110.
To equip health care workers (HCWs) at our tertiary care hospital, we provided fundamental hands-on training in the oxygen therapy and ventilatory management for coronavirus disease-2019 (COVID-19) patients. This research sought to explore how practical training in oxygen therapy for COVID-19 patients affected the knowledge and degree of retention of that knowledge in healthcare workers, six weeks after the session.
Having received approval from the Institutional Ethics Committee, the study was carried out. A structured questionnaire, consisting of 15 multiple-choice questions, was administered to each individual healthcare worker. A 1-hour structured training session on Oxygen therapy in COVID-19 was conducted, and then the same questionnaire was given to the HCWs, with the order of the questions altered. Six weeks later, participants were given a questionnaire, employing a different format and deployed via Google Form, identical to the original.
Following both the pre-training and post-training tests, a total of 256 responses were gathered. Comparing the pre-training test scores, the median was 8, with an interquartile range of 7 to 10, while the post-training test scores showed a median of 12, falling within an interquartile range of 10 to 13. Within the dataset of retention scores, the median value was 11, encompassing a range of 9 to 12. Substantial improvements in scores were observed between the pre-test and retention assessments.
Approximately 89% of the healthcare professionals achieved a substantial increase in their acquired knowledge. The training program's positive impact is clearly seen in the successful knowledge retention of 76% of the healthcare workers. The six-week training period produced a definitive improvement in the acquisition of basic knowledge. We propose a reinforcement training program following six weeks of initial training, to significantly augment retention.
Included in the authorship are A. Singh, R. Salhotra, M. Bajaj, A.K. Saxena, S.K. Sharma, and D. Singh.
A Study on the Lasting Impact of Practical Oxygen Therapy Training for COVID-19 on Healthcare Personnel's Knowledge and Skill Application.